
The estimates on diabetes in this fact sheet were derived from various data systems of the Centers for Disease Control and Prevention (CDC), the outpatient database of the Indian Health Service (IHS), the U.S. Renal Data System of the National Institutes of Health (NIH), the U.S. Census Bureau, and published studies. Estimates of the total number of persons with diabetes and the prevalence of diabetes in 2007 were derived using 2003–2006 National Health and Nutrition Examination Survey (NHANES), 2004–2006 National Health Interview Survey (NHIS), 2005 IHS data, and 2007 resident population estimates. Many of the estimated numbers and percentages of people with diabetes were derived by applying diabetes prevalence estimates from health surveys of the civilian, noninstitutionalized population to the most recent 2007 resident population estimates. These estimates have some variability due to the limits of the measurements and estimation procedures.
The procedures assumed that age-race-sex-specific percentages of adults with diabetes—diagnosed and undiagnosed—in 2007 are the same as they were in earlier time periods—for example, 2003 to 2006—and that the age-race-sex-specific percentages of adults with diabetes in the resident population are identical to those in the civilian, noninstitutionalized population. Deviations from these assumptions may result in over- or under-estimated numbers and percentages.
Prevalence of Diagnosed and Undiagnosed Diabetes in the United States, All Ages, 2007

Source: 2004–2006 National Health Interview Survey estimates projected to year 2007.
Prevalence of Diagnosed Diabetes in People Younger than 20 Years of Age, United States, 2007
Race and Ethnic Differences in Prevalence of Diagnosed Diabetes
Incidence of Diagnosed Diabetes among People Aged 20 Years or Older, United States, 2007

Source: SEARCH for Diabetes in Youth Study.
NHW=Non-Hispanic whites; AA=African Americans; H=Hispanics; API=Asians/Pacific Islanders; AI=American Indians
Incidence of Diagnosed Diabetes in People Younger than 20 Years of Age, United States, 2002 to 2003

Source: SEARCH for Diabetes in Youth Study.
NHW=Non-Hispanic whites; AA=African Americans; H=Hispanics; API=Asians/Pacifi c Islanders; AI=American Indians
Deaths among People with Diabetes, United States, 2006
Complications of Diabetes in the United States
High Blood Pressure
Blindness
Diabetes is the leading cause of new cases of blindness among adults aged 20 to 74 years.
Diabetic retinopathy causes 12,000 to 24,000 new cases of blindness each year.
Kidney Disease
Diabetes is the leading cause of kidney failure, accounting for 44 percent of new cases in 2005.
In 2005, 46,739 people with diabetes began treatment for end-stage kidney disease in the United States and Puerto Rico.
In 2005, a total of 178,689 people with end-stage kidney disease due to diabetes were living on chronic dialysis or with a kidney transplant in the United States and Puerto Rico.
Nervous System Disease
About 60 to 70 percent of people with diabetes have mild to severe forms of nervous system damage. The results of such damage include impaired sensation or pain in the feet or hands, slowed digestion of food in the stomach, carpal tunnel syndrome, erectile dysfunction, or other nerve problems.
Almost 30 percent of people with diabetes aged 40 years or older have impaired sensation in the feet—for example, at least one area that lacks feeling.
Severe forms of diabetic nerve disease are a major contributing cause of lower-extremity amputations.
Amputations
More than 60 percent of nontraumatic lower-limb amputations occur in people with diabetes.
In 2004, about 71,000 nontraumatic lower-limb amputations were performed in people with diabetes.
Dental Disease
Periodontal, or gum, disease is more common in people with diabetes. Among young adults, those with diabetes have about twice the risk of those without diabetes.
Persons with poorly controlled diabetes (A1C > 9 percent) were nearly three times more likely to have severe periodontitis than those without diabetes.
Almost one-third of people with diabetes have severe periodontal disease with loss of attachment of the gums to the teeth measuring 5 millimeters or more.
Complications of Pregnancy
Poorly controlled diabetes before conception and during the first trimester of pregnancy among women with type 1 diabetes can cause major birth defects in 5 to 10 percent of pregnancies and spontaneous abortions in 15 to 20 percent of pregnancies.
Poorly controlled diabetes during the second and third trimesters of pregnancy can result in excessively large babies, posing a risk to both mother and child.
Other Complications
Uncontrolled diabetes often leads to biochemical imbalances that can cause acute life-threatening events, such as diabetic ketoacidosis and hyperosmolar, or nonketotic, coma.
People with diabetes are more susceptible to many other illnesses and, once they acquire these illnesses, often have worse prognoses. For example, they are more likely to die with pneumonia or influenza than people who do not have diabetes.
Persons with diabetes aged 60 years or older are two to three times more likely to report an inability to walk a quarter of a mile, climb stairs, do housework, or use a mobility aid compared with persons without diabetes in the same age group.
Preventing Diabetes Complications
Glucose Control
Studies in the United States and abroad have found that improved glycemic control benefits people with either type 1 or type 2 diabetes. In general, every percentage point drop in A1C blood test results—for example, from 8.0 to 7.0 percent—can reduce the risk of microvascular complications—eye, kidney, and nerve diseases—by 40 percent.
In patients with type 1 diabetes, intensive insulin therapy has long-term beneficial effects on the risk of cardiovascular disease.
Blood Pressure Control
Blood pressure control reduces the risk of cardiovascular disease—heart disease or stroke—among persons with diabetes by 33 to 50 percent, and the risk of microvascular complications—eye, kidney, and nerve diseases—by approximately 33 percent.
In general, for every 10 mm Hg reduction in systolic blood pressure, the risk for any complication related to diabetes is reduced by 12 percent.
Control of Blood Lipids
Preventive Care Practices for Eyes, Feet, and Kidneys
Detecting and treating diabetic eye disease with laser therapy can reduce the development of severe vision loss by an estimated 50 to 60 percent.
Comprehensive foot care programs can reduce amputation rates by 45 to 85 percent.
Detecting and treating early diabetic kidney disease by lowering blood pressure can reduce the decline in kidney function by 30 to 70 percent. Treatment with angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are more effective in reducing the decline in kidney function than other blood pressure lowering drugs.
In addition to lowering blood pressure, ARBs reduce proteinuria, a risk factor for developing kidney disease, by 35 percent—similar to the reduction achieved by ACE inhibitors.
Estimated Diabetes Costs in the United States in 2007
Direct medical costs: $116 billion
Indirect costs: $58 billion—disability, work loss, premature mortality